Hereditary cancer

Gabriel Capella Munar/ Conxi Lázaro Garcia

PRINCIPAL INVESTIGATORS
  • Joan Brunet Vidal
  • Marta Pineda Riu
  • Laura Valle Velasco
  • Barbara Rivera Polo
CLINICAL RESEARCHERS
  • Alexandre Teule Vega
POSTDOCTORAL RESEARCHERS
  • Jose Marcos Moreno Cabrera
  • Jesus Del Valle Dominguez
  • Paula Rofes Terrón
  • Xavier Muñoz Miralles
  • Nuria Dueñas Cid
  • Fátima Marín Nieto
  • Mireia Morell Ginesta
  • Maria Lídia Feliubadaló Elorza
  • Juana Fernandez Rodriguez
  • Nuria Catasus Segura
  • Paula Climent Canto
  • Sara Crespo Yanguas
  • Mariona Terradas Ill
  • Jacopo Boni
  • Ana Filipa Brinco De Oliveira Ponte
PREDOCTORAL RESEARCHERS
  • Hyerim Han
  • Isabel Quintana Gallardo
  • Demetra Kyriacou
  • Carla Roca Grau
  • Clara Nogué Ansón
  • Oscar Mesia Carbonell
  • Edgar Creus Bachiller
  • Sara Ortega Bertran
  • Elisabet Munte Roca
  • Julen Viana Errasti
  • Manuel Torralba Carnerero
  • Anne-Sophie Chong
SCIENTIFIC SUPPORT
  • Carolina Gomez Hernandez
  • Raquel Cuesta Llorente
  • Julia Canet Hermida
  • Gemma Aiza Buscarons
  • Olga Campos Mata
  • Lluis Salvador Hernandez
  • Mireia Ramos Muntada
  • Guillem Campo Fernandez
  • Eva Montes Segura
  • Miriam Fernández I González
  • Cristina Rioja Llerena
MANAGEMENT SUPPORT
  • Guillem Torcal García
  • Patricia Prada Dacasa
  • Iolanda Rubio Carre
Cancer
Oncobell

Scientific production

55

PAPERS

Average IF: 10,102

13

LED PAPERS

Average IF: 8,767

21 PUBLICATIONS IN FIRST DECILE

36 PUBLICATIONS IN FIRST QUARTILE

44 PUBLICATIONS IN OPEN ACCESS

Selected publications

  • Garcia Pelaez,J;Barbosa Matos,R;Lobo,S;Dias,A;Garrido,L;Castedo,S;Sousa,S et al, Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes, Lancet Oncol., 2023;24(1):91-106, doi:10.1016/S1470-2045(22)00643-X
  • Tagliamento,M;Gennari,A;Lambertini,M;Salazar,R;Harbeck,N;Del Mastro,L;Aguilar Company,J et al, Pandemic Phase-Adjusted Analysis of COVID-19 Outcomes Reveals Reduced Intrinsic Vulnerability and Substantial Vaccine Protection From Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Breast Cancer, J. Clin. Oncol., 2023;41(15):2800-2814, doi:10.1200/JCO.22.01667
  • VALLE,L;Monahan,KJ, Genetic predisposition to gastrointestinal polyposis: syndromes, tumour features, genetic testing, and clinical management., Lancet Gastroenterol. Hepatol., 2023;9(1):68-82, doi:10.1016/S2468-1253(23)00240-6
  • Tricarico,R;Madzo,J;Scher,G;Cohen,M;Jelinek,J;Maegawa,S;Nagarathinam,R et al, TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype, Gastroenterology, 2023;164(6):doi:10.1053/j.gastro.2023.01.039
  • Capdevila,J;Hernando,J;Teule,A;Lopez,C;Garcia Carbonero,R;Benavent,M;Custodio,A et al, Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin, Nat. Commun., 2023;14(1):2973-2973, doi:10.1038/s41467-023-38611-5

Research highlights

PROJECTS

8 Granted competitive projects
34 Ongoing competitive projects

1 Started clinical trials
9 Ongoing clinical trials

2 Started non-competitive projects
2 Ongoing non-competitive projects

PUBLISHED WORKS

2 theses
10 Clinical guidelines

NETWORKS

C4CMMRD
CIBERONC
CIMBA
ClinGen
COMPLEXO
CRECE
DIRECt
EHTG
ENIGMA
ERN GENTURIS
SGR GRC-2021
GRE-2021
IMPACT ISCII
INGENIO
IRRDC
NRTO
SOLVE-RD
SPADA
IMPaCT VUSCan
GETTHI

Selected projects

  • FIS22096. Genómica funcional: desarrollo e implementación de una plataforma para el estudio de casos de cáncer hereditario sin resolver. Instituto de Salud Carlos III (ISCIII). Budget: 3.179.990€. 2023-2025. PI: LAZARO GARCIA, CONCEPCION.
  • MCI21007. Polymerase proofREADing-deficient tumors: genetics and immune biology insights for improved predictive MEDicine. Ministerio de Ciencia e Innovación. Budget: 393.250€. 2021-2025. PI: VALLE VELASCO, LAURA.
  • 20MEC021. Modelando el precancer en la deficiencia reparadora de apareamientos erróneos germinal para un seguimiento personalizado basado en la respuesta immune. Ministerio de Ciencia e Innovación. Budget: 338.800€. 2020-2024. PI: Capellá Munar, Gabriel; Marta Pineda.
  • AEC23003. DELINEATING THE INVOLVEMENT OF miRNA BIOGENESIS GENES IN TUMOR DEVELOPMENT (miRNAtude). Asociación Española Contra el Cáncer (AECC). Budget: 300.000€. 2023-2026. PI: RIVERA POLO, BARBARA.
  • 19INT004. The mechanistic basis for constitutional MLH1 methylation (epimutation). NATIONAL INSTITUTES OF HEALTH NIH. Budget: 288872,48. 2019-2024. PI: Capellá Munar, Gabriel.